Publications
iMTA has been at the frontier of health technology assessment in research for over 25 years. We collaborate with all health care stakeholders, while maintaining independence and always publishing results. Find our work below.
Is a 1-year course of methotrexate in patients with arthralgia at-risk for rheumatoid arthritis cost-effective? A cost-effectiveness analysis of the randomised, placebo-controlled TREAT EARLIER trial [View]
Van Mulligen, E., Bour, S. S., Goossens, L. M. A., De Jong, P. H. P., Rutten-Van Mölken, M. & Van Der Helm-Van Mil, A. (2025). Is a 1-year course of methotrexate in patients with arthralgia at-risk for rheumatoid arthritis cost-effective? A cost-effectiveness analysis of the randomised, placebo-controlled TREAT EARLIER trial. Annals of the rheumatic diseases 84(1). Doi: 10.1136/ard-2024-226286
Moving from a registry to a learning health system: A casestudy of a Dutch prostate cancer registry [View]
Tom Belleman, Jeroen van Wijngaarden, Malou C.P. Kuppen, Saskia de Groot, Kim J. M. van der Velden, Dianne Bosch, Inge M. van Oort, Carin Uyl – de Groot, Welmoed van Deen (2025). Moving from a registry to a learning health system: A casestudy of a Dutch prostate cancer registry. Research Report. doi.org/10.1002/lrh2.10476
Avoiding Error and Finding the Right Balance in European Health Technology Assessments: Insights Generated by the European Access Academy [View]
Elaine Julian, Tom Belleman, Maria João Garcia, Robin Doeswijk, Rosa Giuliani, Bernhard J. Woermann, Daniel Widmer, Patrick Tilleul, Ruben Casado-Arroyo, Valentina Strammiello, Kate Morgan, Marcus Guardian, Michael Ermisch, Renato Bernardini, Fabrizio Gianfrate, Stefano Capri, Carin de Groot, Mira Pavlovic, Jörg Ruof, Maureen van Molken (2025). Avoiding Error and Finding the Right Balance in European Health Technology Assessments: Insights Generated by the European Access Academy. Journal of Market Access and Health Policy 5 (1-16). jmahp-13-00006-v2.pdf
Treatment-related toxicity, utility and patient-reported outcomes of head and neck cancer patients treated with proton therapy: A longitudinal study [View]
Hsuan Chen, Y., Kroesen, M., Hoogeman, M., Versteegh, M., Uyl-de Groot, C. & Blommestein, H. M (2025). Treatment-related toxicity, utiity and patient-reported outcomes of head and neck cancer patients treated with proton therapy: A longitudinal study. Clinical and Translational Radiation Oncology. DOI; 10.1016/j.ctro.2025.100913
Cost-effectiveness of treatment sequences for BRAF-mutant advanced melanoma in the Netherlands using a health economic model [View]
Blommestein H, Groot S de, Leeneman B, Uyl-de Groot CA, Haanen JBAG, Wouters M, Arts WJM, Berkemortel van den B, Blokx PF, Boers-Sonderen M et al (2025). Cost-effectiveness of treatment sequences for BRAF-mutant advanced melanoma in the Netherlands using a health economic model. European Journal of Cancer 218. Doi: 10.1016/j.ejca.2024.115071
Comparison of Management and Outcomes of Hip Fractures Among Low- and High-Income Patients in Six High-Income Countries [View]
Nicole Huang, Laura A Hatfield, Saeed Al-Azazi, Pieter Bakx, Amitava Banerjee, Nitzan Burrack, Yu Chin Chen, Christina Fu, Carlos Godoy Junior, Renaud Heine, Dennis T. Ko, Lisa M Lix, Victor Novack, Laura Pasea, Feng Qiu, Bheeshma Ravi, Therese A Stukel, Carin de Groot, Peter Cram, Bruce E. Landon (2024). Comparison of Management and Outcomes of Hip Fractures Among Low- and High-Income Patients in Six High-Income Countries. Journal of General Internal Medicine. Doi: 10.1007/s11606-024-09274-9
Including carer health-related quality of life in NICE health technology assessments in the United Kingdom [View]
Kanters TA, van Hezik-Wester V, Boateng A, Cranmer H, Kvamme I, Santi I, Al-Janabi H, van Exel J (2024). Including carer health-related quality of life in NICE health technology assessments in the United Kingdom. Cambridge University Press. Doi: 10.1017/S1744133124000124.
COMPAR-EU Recommendations on Self-Management Interventions in Type 2 Diabetes Mellitus [View]
Jessica Beltran, Claudia Valli, Melixa Medina-Aedo, Carlos Canelo-Aybar, Ena Niño de Guzmán, Yang Song, Carola Orrego, Marta Ballester, Rosa Suñol, Janneke Noordman, Monique Heijmans, Georgios Seitidis, Sofia Tsokani, Katerina Maria Kontouli, Christos Christogiannis, Dimitris Mavridis, Gimon de Graaf, et al (2024). COMPAR-EU Recommendations on Self-Management Interventions in Type 2 Diabetes Mellitus. Healthcare 12(4), 483. Doi.org/10.3390/healthcare12040483
Economic evaluation of remote monitoring of patients with an implantable cardiac defibrillator (REMOTE-CIED study)
Gimon de Graaf, Ivy Timmermans, Mathias Meine, Marco Alings, Susanne S Pedersen, Philippe Mabo, Edgar Zitron, Ken Redekop, Henneke Versteeg (2024). Economic evaluation of remote monitoring of patients with an implantable cardiac defibrillator (REMOTE-CIED study). Journal of Telemedicine and Telecare. Doi/10.1177/1357633X221129176
The Cost-Effectiveness of Seizure Dogs for Persons Living With Severe Refractory Epilepsy: Results From the EPISODE Study [View]
Van Hezik-Wester V, de Groot S, Kanters T, Wagner L, Ardesch J, Brouwer W, Corro-Ramos I, van Exel J, Versteegh M (2024). The Cost-Effectiveness of Seizure Dogs for Persons Living With Severe Refractory Epilepsy: Results From the EPISODE Study. Value Health. Doi: 10.1016/j.jval.2024.07.020. Epub ahead of print. PMID: 39127247.